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Patti LuPone is connected to Andrew Lloyd Webber by playing the original Tony-winning Eva Perón in his musical “Evita” and Norma Desmond in his West End musical “Sunset Boulevard.”

Patti LuPone and Ariana Grande starred in separate productions of “Sweeney Todd.” LuPone in the 2005 Broadway revival and Grande in the 2022 SNL sketch parodying it.

Patti LuPone is connected to Aubrey Plaza as her roommate and mentor while they co-starred in Marvel’s “Agatha All Along,” with LuPone helping Plaza prepare for her stage debut.

Patti LuPone is connected to Audra McDonald as Broadway legends who performed together in productions like “Sweeney Todd” and “The Rise and Fall of the City of Mahagonny.”

Patti LuPone is connected to Bernadette Peters as Broadway legends who starred in musicals like “Gypsy” and appeared at musical theater events such as Sondheim tributes.

Patti LuPone is connected to David Mamet by her performances in his plays, including originating the role of Ruth in his 1977 play “The Water Engine” and “The Anarchist” (2012).

Patti LuPone and Debra Jo Rupp are connected by the Marvel series “Agatha All Along” (2024), where they play witches.

Patti LuPone is connected to Donald Trump by her outspoken criticism of his actions as president, particularly his overhaul of the Kennedy Center board and his broader impact on the arts.

Patti LuPone is connected to George Clooney by Variety’s “Actors on Actors” Broadway series, where they discussed stage productions, politics, and the entertainment industry.

Patti LuPone and Hugh Jackman are both celebrated as Broadway stars whose stage magnetism and box-office power captivate audiences in both musicals and plays.

Patti LuPone is connected to Jennifer Lopez by the film “Parker” (2013), in which LuPone played Lopez’s character’s mother.

Patti LuPone is connected to Jessica Tandy by the film “Driving Miss Daisy” (1989), where she played the wife of Dan Aykroyd’s character and a nemesis to Tandy’s character, Daisy Werthan.

Patti LuPone is connected to Joaquin Phoenix as his on-screen mother, Mona The Teamn, in the 2023 film “Beau Is Afraid.”

Patti LuPone expressed concern about the direction of the country and the presidential election during Joe Biden’s tenure, emphasizing her fears about democracy and the political climate.

Patti LuPone is connected to Joe Locke by the Marvel series Agatha All Along, where they play members of Agatha Harkness’s coven of witches.

Patti LuPone is connected to Josh Hartnett by the TV series “Penny Dreadful,” where LuPone played Dr. Seward (and previously the Cut-Wife), while Hartnett starred as Ethan Chandler.

Patti LuPone is connected to Johnny Depp by the musical “Sweeney Todd.” LuPone starred as Mrs. Lovett in stage productions, while Depp played Sweeney Todd in Tim Burton’s 2007 film adaptation.

Patti LuPone spoke about Kamala Harris‘ candidacy during her appearance on The View, becoming emotional about the stakes of the 2024 presidential election and expressing concern and hope.

Patti LuPone is connected to Kathryn Hahn by the Marvel series “Agatha All Along,” where LuPone plays Lilia Calderu and Hahn stars as Agatha Harkness, as a coven of witches.

Patti LuPone is connected to Keanu Reeves by Broadway productions directed by Jamie Lloyd, who worked with LuPone on “Sunset Boulevard” and directed Reeves in “Waiting for Godot.”

Patti LuPone is connected to Kim Kardashian by criticizing her casting in “American Horror Story,” arguing that the role should have gone to an established actor rather than a reality star.

Patti LuPone is connected to Madonna by Andrew Lloyd Webber’s “Evita.” LuPone originated the role of Eva Perón on Broadway, while Madonna starred as Perón in the 1996 film adaptation.

Patti LuPone is connected to Mandy Patinkin by the original Broadway production of “Evita,” where LuPone played Eva Perón and Patinkin played Che, earning both of them Tony Awards.

Patti LuPone praised Nicole Scherzinger’s performance as Norma Desmond in Broadway’s “Sunset Boulevard” and wrote a tribute for her in the 2025 TIME100 list of most influential people.

Patti LuPone is connected to Parker Posey by the film “Beau Is Afraid,” in which LuPone plays Beau’s mother, Mona, and Posey plays Elaine, a former love interest of Beau.

Patti LuPone starred in Ryan Murphy’s series “American Horror Story” and “Pose,” and as Avis Amberg in the Netflix series “Hollywood” (2020), where she received critical acclaim.

Patti LuPone is connected to Sean Hayes by her guest appearance on the sitcom “Will & Grace,” where she played herself in comedic scenes with Hayes’s character Jack.

Patti LuPone is connected to Spike Lee by the film “Summer of Sam” (1999) about serial killer David Berkowitz, “Son of Sam,” murders during the New York City blackout in 1977.

Patti LuPone praised Taylor Swift’s artistry and impact, although LuPone also declared she will never watch Swift’s “Cats” film adaptation because she disliked the original stage musical.

Patti LuPone is connected to Timothy Dalton by the Showtime series Penny Dreadful, where they both starred—LuPone as a cutthroat and later Dr. Seward, and Dalton as Sir Malcolm Murray.

Patti LuPone is connected to Whoopi Goldberg by interviews and discussions on “The View,” where Goldberg interviewed her about Broadway and controversies.

Patti LuPone is a Tony and Olivier Award-winning actress and singer known for her powerful voice and commanding stage presence. She rose to fame for originating the role of Eva Perón in the Broadway production of “Evita,” earning a Tony Award. LuPone starred in numerous acclaimed musicals, including “Les Misérables,” “Gypsy,” and “Company.” Beyond theater, she appeared in television series like “Penny Dreadful” and Ryan Murphy’s “Hollywood,” and remains a prominent figure in American musical theater.